Hepatitis B Envelope Antibody (HbeAb), Serum
- Reporting Time:
- 6 Hrs
- Specimen Type:
- Home Collection:
- No special preparation required
Parameters Covered in the above test : 3
Hepatitis B Envelope Antibody (HBeAb)
HBeAb levels can be used to monitor the progress of hepatitis B viral infection
HBe Antibody produced against Hepatitis ôB eÆÆ Antigen. The positive test indicates chronic infection. It is helpful to monitor the effectiveness of its treatment.
Hepatitis B e antigen (HBeAg), Antibody to Hepatitis B e antigen (anti-HBe) are found in hepatitis B viral infection. HBeAg is first detectable in the early phase of hepatitis B viral infection, after the appearance of hepatitis B surface antigen (HBsAg). The levels of both antigens increase during the period of viral replication in acute infection. Seroconversion from HBeAg to anti-HBe during acute hepatitis B infection is indicative of resolution of infection and a reduced level of infectivity. HBeAg result is negative during early acute infection prior to HBV viral replication or early convalescence. HBeAg levels fall below the detectable levels and the presence of anti-HBe serves to differenciate between Seroconversion and convalescence . In chronic hepatitis B patients negative HBeAg in serum, positive anti-HBe and these patients may also be positive for serum hepatitis B virus DNA. HBe antigen/antibody seroconversion is used as an indicator of virological response when treating patients with chronic hepatitis B infection.
1. What are the different types of Hepatitis infection?
Hepatitis A virus, Hepatitis E virus, Hepatitis B surface Antigen, Hepatitis C Virus. These diseases caused by different types of viruses. Hepatitis A virus is transmitted through faeco-oral route by drinking contaminated water or Food. The disesase is acute not chronic. Hepatitis B and C viral infections begin as acute, but in some persons the virus remains in the body and become chronic.
2. What is the mode of Transmission of Hepatitis B virus?
1. During Birth spread from an infected mother to child
2. Sexual transmission.
3. By Sharing needles, syringes, or other drug-injection equipment
4. By direct contact with the blood or open wounds of an infected person
5. Exposure to blood from needle sticks or other sharp instruments.
3. What are different types of Hepatitis markers to evaluate Hepatitis B disease condition?
HBs Ag: This is the first antigen appeared during Acute infection. It is also present in the chronic stage.
Hepatitis B core Antibody Total(Anti-HBC): HBc antibody produced by the body against Hepatitis B virus called the ”core antigen.”
A positive test means: A person is either currently infected with the Hepatitis B virus or was infected in the past.
Hepatitis B core IgM antibody(Anti-HBc IgM): It is used to detect acute infection.
Hepatitis “B e’’ Antigen: High levels of HBe Ag present in the blood during acute Hepatitis B virus infection. This test is used to monitor the effectiveness of treatment.
Hepatitis “B e’’ Antibody: This is Antibody produced against Hepatitis “B e’’ Antigen. The positive test indicates chronic infection.
Hepatitis B viral Load: The test is used to diagnose the prescence of Hepatitis B viral DNA in the blood. High levels of viral load is the indication of acute infection. This test is used to monitor the effectiveness of treatment.
4. What are the preventive measures used for Hepatitis B virus infection?
Vaccination with Hepatitis B is the best preventive measure to protect against Hepatitis B virus infection. After vaccination, antibodies are produced against virus and gives protection.