Dengue Ig G & Ig M Antibody Rapid, Serum

Dengue fever testing is used to determine whether a person with signs and symptoms and recent potential exposure has been infected with the dengue virus. The infection is difficult to diagnose without laboratory tests because symptoms may initially resemble those of other diseases, such as chikungunya infection. Two primary types of testing are available: Antibody testsûthese tests are primarily used to help diagnose a current or recent infection. They detect two different classes of antibodies produced by the body in response to a dengue fever infection, IgG and IgM. Diagnosis may require a combination of these tests because the body's immune system produces varying levels of antibodies over the course of the illness. IgM antibodies are produced first and tests for these are most effective when performed at least 7-10 days after exposure. Levels in the blood rise for a few weeks, then gradually decrease. After a few months, IgM antibodies fall below detectable levels. IgG antibodies are produced more slowly in response to an infection. Typically, the level rises with an acute infection, stabilizes, and then persists long-term. Individuals who have been exposed to the virus prior to the current infection maintain a level of IgG antibodies in the blood that can affect the interpretation of diagnostic results. Molecular testing (polymerase chain reaction, PCR)ûthis type of test detects the genetic material of the dengue virus in blood up to 5 days after symptom onset (fever).

Can dengue fever be prevented?

Currently, there is no immunization that will prevent a person from contracting dengue fever if exposed to the virus. Limiting exposure to the virus depends upon protecting against mosquito bites. When traveling in tropical climates, wear insect repellent that contains DEET and long sleeved-shirts and long pants. Stay indoors during dawn and dusk when mosquitoes are most active.

Can dengue fever be passed from person to person?

No, the virus is not spread by person-to-person contact or by exposure to respiratory secretions. The virus is spread when a mosquito bites an infected person, then bites a healthy person. It may be transmitted in rare cases through a blood transfusion, organ donation, or mother to fetus.

If I have had dengue fever, can I get it again?

Yes. There are four serotypes of the dengue virus. There is no cross-protective immunity to all dengue viruses when you are exposed to one serotype. In addition, a subsequent infection with a dengue fever virus is usually associated with more severe disease.