Protein S Functional, Sodium Citrate Whole Blood
- Reporting Time:
- 3 Days
- Specimen Type:
- Home Collection:
- No special preparation required
To determine protein C deficiency and helps to evaluate inappropriate thrombus (blood clot) formation.
When there is a family history of protein C deficiency, when there is inapproriate and unexplained thrombus (blood clot) formation and when there is any clotting disorder.
1. Can protein C and protein S test be done when the patient is on anticoagulant therapy?
Anticoagulant drugs may alter protein C and protein S levels and/ or interfere with the activity assays. Hence it is advised to stop the treatment for a limited period of time, before the test is done.
2. Can protein C and protein S levels be increased?
If the deficiency of protein C and/ or protein S levels is temporary as in pregnancy and infection, the levels return to normal by themselves. Protein C or protein S deficiency due to liver diseases or vitamin K deficiency are treated by addressing the underlying condition. In inherited cases lowering other clotting risk factors (like smoking, oral contraceptive intake etc.) is advised.
3. Should relatives of patients with inherited protein C or protein S deficiency also be tested?
Not required, as the penetrance of genes is low. However it is done if there is a strong family history or a history of developing early age thrombosis.